tooluniverse-variant-interpretation

The skill concept is largely coherent with its stated purpose of ACMG-based variant interpretation augmented by structural and literature evidence. Its footprint is proportionate for a specialized clinical genomics tool. Key risk areas concern data governance (PHI handling, auditing, and access controls), provenance/versioning of many external data sources, and careful separation of somatic (COSMIC) vs germline evidence to avoid misclassification. No explicit credential-exploitation or download-execute patterns are present; the footprint is mainly read/aggregate and compute, with outputs intended for clinical reports. Overall, the design is BENIGN with notable security/compliance caveats that should be addressed before deployment.