polars-bio

Use this skill for genomic interval arithmetic and bioinformatics file I/O through Polars and DataFusion. It targets polars-bio 0.36.0, tested with Polars 1.44.2 on Python 3.13. The upstream package requires Polars >=1.37.1, PyArrow >=23.0.1,<25, DataFusion >=53,<54 and polars-config-meta >=0.3.2,<1. Keep this environment separate from packages needing incompatible Arrow or DataFusion releases.

uv pip install "polars-bio==0.36.0" "polars==1.44.2"
# Optional pandas interoperability (requires pandas >=3):
uv pip install "polars-bio[pandas]==0.36.0" "polars==1.44.2"

Verify new releases against the official release notes and package requirements. The examples below with named files are templates: substitute actual files and check their schemas. The synthetic interval example and small local format round trips were executed during this review.